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pentobarbital will reduce the level or impact of mifepristone by impacting hepatic/intestinal enzyme CYP3A4 metabolism. Use Caution/Observe. CYP3A4 inducers have not been studied, coadministration not recommended by manufacturerpentobarbital will minimize the extent or outcome of acalabrutinib by impacting hepatic/intestinal enzyme CYP3A4 metabolis